In the genesis of humanity, God imparted the knowledge of names to mankind, designating them as successors on earth, a shared responsibility for both men and women. The establishment of the family institution by early societal figures marked the genesis of societal construction and management involving both genders. The presence of women alongside men is deemed essential in social life, contrary to historical perceptions portraying women as emotionally-driven and relegating them to the private sphere, perpetuating a civilization lacking maternal nurturing. Through an ontological exploration of the narratives of Virgin Mary and the Queen of Sheba in the Holy Quran, this essay advocates for the harmonious synergy between female and male rationalities in civilization-building endeavors. This cooperation aims to provide a conducive environment for the advancement of female-driven rationality in governing human societies, characterized by attributes such as fostering life, growth, protection, care, security, spirituality, and peace.